SUN-126 Discordantly High Hemoglobin A1c Caused by Hemoglobin Wayne Variant
نویسندگان
چکیده
منابع مشابه
Measurement of Hemoglobin A1c
Evaluation of glycemia is used for the diagnosis and management of patients with diabetes. Glucose and hemoglobin A1c (HbA1c) provide complementary information and both are used to assess an individual’s glycemic status. The concentration of glucose in the blood indicates the subject’s glycemia at the time of blood sampling. However, blood glucose concentrations are modified by numerous factors...
متن کاملUnexpected hemoglobin A1c results.
A 52-year-old woman with a medical history of hepatitis B, hyperlipidemia, hypertension, anemia, and depression presented to the internal medicine clinic for a routine visit. Laboratory tests 3 months previously had revealed an impaired fasting glucose concentration of 5.9 mmol/L (106 mg/dL) [reference interval, 3.9 –5.6 mmol/L (70 –100 mg/dL)]. Therefore, a hemoglobin (Hb) A1c analysis was per...
متن کاملHemoglobin A1c: Clinical applications and analytical considerations
Diabetes Mellitus (DM) is the most common disorder of carbohydrate metabolism. Hyperglycemia is the common feature of DM. Hyperglycemia causes cardiovascular, renal, ocular, and peripheral nerve disorders in patients with diabetes. Glycemic regulation plays an essential role in controlling these complications. Thus, evaluation of the glycemic control status is crucial in the management of DM. H...
متن کاملA review of variant hemoglobins interfering with hemoglobin A1c measurement.
Hemoglobin A1c (HbA1c) is used routinely to monitor long-term glycemic control in people with diabetes mellitus, as HbA1c is related directly to risks for diabetic complications. The accuracy of HbA1c methods can be affected adversely by the presence of hemoglobin (Hb) variants or elevated levels of fetal hemoglobin (HbF). The effect of each variant or elevated HbF must be examined with each sp...
متن کاملQuantitation of hemoglobin A1a+b and hemoglobin A1c by automated "high-performance" liquid chromatography.
The glycosylated hemoglobins A1a+b and A1c have been rapidly and precisely quantitated in 5-micro L samples of human blood hemolysate (approximately 240 micrograms of hemoglobin) by cation-exchange column chromatography. Total chromatographic is 22.0 min. Proportions of Hb A1c range from 3.85 to 6.71% in normal individuals and from 4.23 to 19.90% in diabetic subjects. Within-day variation was 1...
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ژورنال
عنوان ژورنال: Journal of the Endocrine Society
سال: 2019
ISSN: 2472-1972
DOI: 10.1210/js.2019-sun-126